BIO 280 - Pathophysiology

Credits: 4
Instructional Contact Hours: 4

1. Demonstrate the understanding of general processes in pathophysiology.

1. Explain the role of pathophysiology in disease progression.
2. Describe Meiosis alterations.
3. Describe Genetic disorders.
4. Describe common cellular adaptations and possible reasons for the occurrence of each.
5. Explain common causes of cell damage.
6. Describe Apoptosis and Necrosis and the types of Necrosis.
7. Describe the cellular stress response.
8. Describe precancerous cellular changes.
9. Describe initiation, progression, and transformation of cancerous cells.
10. Explain the unique features of a cancer cell.
11. Describe the causes and effects of dehydration.
12. Describe the causes and effects of electrolyte imbalance.
13. Describe metabolic and respiratory acidosis and alkalosis.
14. Describe the causes and the compensation reactions in respiratory and metabolic acidosis and alkalosis.

2. Demonstrate the understanding of healing.

1. Explain the role of normal defenses in preventing diseases.
2. Describe capillary-tissue exchange during the inflammatory response.
3. Describe the steps involved with the inflammatory response.
4. Describe the types of healing and list the factors that affect healing.
5. Describe the local and systemic effects of inflammation.
6. Explain the effects of chronic inflammation.
7. Identify the classification of burns.

3. Demonstrate the understanding of immunity disorders.

1. Describe the four types of hypersensitivity reactions.
2. Describe Alloimmunity.
3. Compare tissue transplant rejection and graft-vs-host disease.
4. Describe immunodeficiency.
5. Describe causative agents of infections.

4. Demonstrate the understanding of neurological disorders.

1. Explain the causes of pain and describe the pain pathway.
2. Compare acute and chronic pain.
3. Explain Arousal and Consciousness and how injury affects these conditions.
4. Describe cerebrovascular disorders.
5. Describe infections of the CNS.
6. Describe CNS and spinal cord trauma.
7. Describe congenital neurological disorders.
8. Describe a seizure and the types of seizures.
9. Describe chronic degenerative diseases.
10. Describe motor function diseases.
11. Describe dementia.

5. Demonstrate the understanding of endocrine disorders.

1. Explain the mechanism of hormonal regulation by negative feedback mechanism under normal and abnormal conditions.
2. Describe alterations in hormone concentration, target cell reception, and responses.
3. Describe pituitary hormone disorders.
4. Describe type 1 type 2 diabetes mellitus.
5. Describe Parathyroid disorders.
6. Describe Thyroid disorders.
7. Describe Adrenal disorders.

6. Demonstrate the understanding of blood disorders.

1. Describe the types of anemia.
2. Describe polycythemia.
3. Describe excessive bleeding and Hemophilia.
4. Describe blood clotting disorders and DIC.
5. Describe lymphadenopathy.
6. Describe infectious mononucleosis.
7. Describe acute and chronic leukemia.
8. Describe Hodgkin's and Non-Hodgkin's lymphomas.

7. Demonstrate the understanding of cardiovascular system disorders.

1. Describe coronary artery disease.
2. Describe angina pectoris and myocardial infarction.
3. Describe atherosclerosis.
4. Describe arrhythmias.
5. Describe heart valve disorders.
6. Describe congestive heart failure and the effects of left-sided vs. right-sided failure.
7. Describe rheumatic heart disease, endocarditis, and pericarditis.
8. Describe congenital heart diseases.
9. Describe hypertension.
10. Describe peripheral vascular diseases.
11. Describe shock.

8. Demonstrate the understanding of digestive system disorders.

1. List common manifestations of digestive system disorders.
2. List and describe common symptoms of digestive system disorders.
3. Describe motility disorders.
4. Describe gastritis and gastroenteritis.
5. Describe peptic ulcers.
6. Describe digestive obstruction.
7. Describe celiac disease.
8. Describe Crohn's disease
9. Describe ulcerative colitis.
10. Describe diverticulosis.
11. Describe portal hypertension, jaundice, hepatitis, and cirrhosis.

9. Demonstrate the understanding of respiratory system disorders.

1. List and describe common symptoms of respiratory system disorders.
2. Describe common respiratory tract infections.
3. Describe ventilation vs. perfusion.
4. Describe restrictive lung diseases.
5. Describe obstructive lung diseases.
6. Compare obstructive from restrictive lung disorders.
7. Describe Asthma, Chronic Bronchitis, and Emphysema.
8. Describe pulmonary edema.
9. Describe atelectasis.
10. Describe pneumothorax.
11. Describe pneumoconiosis.
12. Describe chest wall injuries.
13. Describe respiratory distress syndrome.
14. Describe acute respiratory failure.

10. Demonstrate the understanding of urinary system disorders.

1. List main diagnostic tests to recognize urinary disorders.
2. List and describe common symptoms of urinary system disorders.
3. Describe urinary tract obstruction.
4. Describe urinary tract infection.
5. Describe PID, Chlamydia, Gonorrhea, Syphilis, and Herpes.
6. Describe incontinence and list examples of causes of incontinence.
7. Describe cystitis and pyelonephritis.
8. Describe glomerulonephritis and nephrotic syndrome.
9. Describe vascular disorders of the kidney.
10. Describe acute vs. chronic renal failure.